Regeneration-specific expression pattern of three posterior Hox genes
نویسندگان
چکیده
منابع مشابه
Planarian Hox genes: novel patterns of expression during regeneration.
Platyhelminthes are widely considered to be the sister group of coelomates (Philippe, H., Chenuil, A. and Adoutte, A. (1994)Development 1994 Supplement, 15-24) and the first organisms to show bilateral symmetry and cephalization. Within this phylum, the freshwater planarians (Turbellaria, Tricladida) have been used as model systems for studying bidirectional regeneration (Slack, J. M. W. (1980)...
متن کاملAnalysis of Hox-4.5 and Hox-3.6 expression during newt limb regeneration: differential regulation of paralogous Hox genes suggest different roles for members of different Hox clusters.
Adult urodele amphibians can regenerate their limbs and tail. Based on their roles in other developing systems, Hox genes are strong candidates for genes that play a role in regulating pattern formation during regeneration. There are four homologous clusters of Hox genes in vertebrate genomes. We isolated cDNA clones of two newt homeobox genes from homologous positions within two Hox clusters; ...
متن کامل21-P032 Regulation of chondrocyte differentiation by posterior Hox genes
It is well known that activin-treated presumptive ectoderm, which is generally called as animal cap, in amphibian differentiates into various types of tissues and organs such as notochord, muscle, heart, and kidney. However, there has been no report that primordial germ cells are induced by activin treatment for animal caps. Anterior or posterior axial mesoderms can be, respectively, induced by...
متن کاملAberrant Expression of Posterior HOX Genes in Well Differentiated Histotypes of Thyroid Cancers
Molecular etiology of thyroid cancers has been widely studied, and several molecular alterations have been identified mainly associated with follicular and papillary histotypes. However, the molecular bases of the complex pathogenesis of thyroid carcinomas remain poorly understood. HOX genes regulate normal embryonic development, cell differentiation and other critical processes in eukaryotic c...
متن کاملRegeneration, repair and remembering identity: the three Rs of Hox gene expression.
Hox genes encode transcription factors that specify embryonic positional identity in cells and guide tissue differentiation. Recent advances have greatly increased our understanding of the epigenetic mechanisms that ensure the faithful expression of Hox genes in adult cells and which involve the interplay of histone methylation, demethylation and intergenic transcription of long non-coding RNAs...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2003
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.10231